SvanovirF.Hepatica -Ab

ELISA Test for detection Antibodies Fasciola Hepatica

Ref.: 16-2930-02

SVANOVIR®F.hepatica-Ab on the E/S protein and detects antibodies to Fasciola hepatica (F. hepatica) in dairy and beef cattle. The assay has been validated using naturally infected populations and is the first test enabling the identification of herds and individuals that exceed an acceptable level of infection.


SVANOVIR®F.hepatica-Ab on the E/S protein and detects antibodies to Fasciola hepatica (F. hepatica) in dairy and beef cattle. The assay has been validated using naturally infected populations and is the first test enabling the identification of herds and individuals that exceed an acceptable level of infection.
YOUR CHALLENGE is a subclinical disease resulting in production loss.
Cattle take up infectious stages of F. hepatica while grazing in wet pastures. Flukes affect the liver but fasciolosis is primarily subclinical with no obvious clinical signs. However, production loss increases in correlation to the numbers of Flukes affecting the liver. In Western Europe herd-level prevalence varies between 30-80%.

YOUR GOAL is to identify herds with F. hepatica induced production losses.
F. hepatica cannot be eradicated, but it is possible to control the impact of infection on production output. Monitoring and maintaining herd infection at an acceptable level, where there is no loss of production, is a new way to manage fasciolosis. In order to ensure rational and selective use of anthelminthic treatment, it is essential that the effectiveness of the control strategies is monitored.
First test for economic diagnosis of F. hepatica.
Enables monitoring of the effectiveness of control strategies.
Thoroughly validated on naturally infected populations.

High sample throughput
- effective screening of herds and numerous individuals
Triple functionality
- milk, serum and meat juice samples can be run in the same assay.
Effective handling - ready-to-use conjugate and flexible incubation times (short overnight).

SVANOVIR® F. hepatica-Ab has been validated in comprehensive studies on naturally infected populations. In these studies, a strong correlation between infection (number of Flukes in the liver), antibody levels to F. hepatica, and loss of milk yield or carcass weight was demonstrated
(Charlier et al., 2007; 2009). Cut-off values were determined to indicate when production loss from F. hepatica infection becomes economically relevant. Furthermore, those individuals could be identified that had most benefit from anthelmintic treatment (Charlier et al., 2012).
SVANOVIR® F. hepatica-Ab has been validated in dairy and beef cattle using milk and serum/meat juice samples respectively, thus enabling the monitoring of fasciolosis at several different stages of the production chain, i.e., at the farm, at dairies and at slaughter.

Milk ( dairy cows)

Serum, meat juice (beef cattle)

SVANOVIR F. Hepatica - Ab.

Antibody levels

 

ODR < Cut - off

 

ODR > Cut - off

Number of flukes in liver*

None to low

Medium to high

Results indicate

No economic impact

Economic impact

Decision-making support

No/Low exposure. No control needed or Control is effective.

Medium/High exposure. Control nedeed or ineffective control.

Codigo Muestras Placas Formato
16-2930-02 Especie: BOVINO   ; Muestras: Suero/Plasma, Jugo de carne, Leche (individuos o en bulk); Numero muestras:   184 (excluidos pocillos para controles) 2 TIRAS
Oficina Central Calle José Echegaray 8
P.A.E. Casablanca I, Local 1-3 - 28100 Alcobendas
Madrid. España